Secretariat, Alumni Association, IDAC
Date	Wednesday, 7 August 2024, 10:30～11:30
Room	7th Floor, Large-size Conference Room, IDAC Center for Basic Aging Research
Title	Ultrafast high frequency ultrasound blood flow imaging for pre-clinical and clinical applications
Speaker	Professor Chih-Chung Huang
Affiliation	National Cheng Kung University, Department of Biomedical Engineering, Taiwan
Organizer	Tomoyuki Yambe (Department of Medical Engineering and Cardiology/Department of Pre-Clinical Evaluation, ext 8517) Tasuyuki Shiraisi (Department of Pre-Clinical Evaluation, ext 8517)
Abstract	To date, the operational frequency of the ultrafast ultrasound imaging is around 2 to 18 MHz, which provides sufficient image resolution with an appropriate imaging depth for clinical applications. However, the spatial resolution of ultrasound imaging can be improved by using high frequency ultrasound imaging (HFUS, >30 MHz), for example, 50 MHz ultrasound imaging provides lateral and axial resolutions of 100 and 20 μm, respectively. Recently, single element and array transducers HFUS imaging systems are commercially available at a center frequency up to 50 MHz. However, the HFUS with an ultrafast imaging ability is still lacking currently. In this talk, ultrafast HFUS imaging combining a high frequency array transducer (~40 MHz) with a programmable ultrasound imaging has been proposed. Due to the high imaging resolution ability of HFUS, this ultrafast HFUS imaging is suitable for superficial tissue imaging of human and small animal for gene research and cancer studies. Therefore, high-resolution ultrasound elastography and super resolution blood flow imaging without micro-bubble are currently available for biomedical applications, such as high resolution elastography for human cornea, skin, hand tendon, and mouse brain as well as super resolution blood flow imaging for small animal applications in nerve, brain, heart, and kidney.